Home Medizin Eine Studie legt nahe, dass das Gehirn möglicherweise einen einzigen gemeinsamen Bauplan nutzt, um die frühe Entwicklung zu steuern

Eine Studie legt nahe, dass das Gehirn möglicherweise einen einzigen gemeinsamen Bauplan nutzt, um die frühe Entwicklung zu steuern

von NFI Redaktion

In a new study published in the Proceedings of the National Academy of Sciences (PNAS), researchers from the University of Minnesota Medical School investigated brain development to understand how different areas of the brain specialize in processing information such as vision, sound, touch, and planning.

The study revealed that different areas of the brain initially have a similar organization and are not already specialized in early development. This suggests that the brain may use a single common blueprint to guide early development.

„Throughout life, the brain continuously builds upon the foundations laid in early development. This strong similarity in early development across very different areas of the brain suggests that neurological developmental disorders – such as autism or schizophrenia, which affect many different parts of the nervous system – may act similarly in these different brain areas.“

Gordon Smith, Ph.D., Assistant Professor at the U of M Medical School and lead researcher of the study

Dr. Smith is also a member of the Medical Discovery Team for Optical Imaging and Brain Research.

In collaboration with the Frankfurt Institute of Advanced Studies, the research team utilized advanced optical imaging techniques to measure spontaneous activity in different areas of the brain. They found that even in different parts of the brain – such as those responsible for hearing, vision, and tactile sensations, as well as areas associated with thinking in the front and back of the brain – the activity in networks of brain cells during early development showed a very similar organization. Researchers found that nerve cells in these areas work together in small, synchronized groups. These groups are part of larger networks that span millimeters in every part of the brain.

„This type of organization has long been a hallmark of visual brain areas, but it was a surprise to find it in other regions as well – particularly in non-sensory regions like the prefrontal cortex,“ said Dr. Smith.

Ongoing research will examine other brain regions at different developmental stages to determine how the common blueprint identified in this study changes over time.

This study was funded by the National Eye Institute of the National Institutes of Health [R01EY030893-01], Whitehall Foundation, National Science Foundation, and Federal Ministry of Education and Research.

Source:

University of Minnesota Medical School

Journal Reference:

Powell, NJ, et al. (2024). Shared modular architecture across different cortical areas in early development. Proceedings of the National Academy of Sciences. doi.org/10.1073/pnas.2313743121.

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