Home Medizin Altersbasierter Vergleich der TAVR-Ergebnisse bei vietnamesischen Patienten mit Aortenstenose

Altersbasierter Vergleich der TAVR-Ergebnisse bei vietnamesischen Patienten mit Aortenstenose

von NFI Redaktion

Announcement of a new article publication for Cardiovascular Innovations and Applications journal. The increasing number of elderly patients with severe aortic valve stenosis undergoing transcatheter aortic valve replacement (TAVR) has raised concerns about their clinical outcomes compared to younger populations. This study evaluated the outcomes of TAVR based on age group (<80 or ≥80 years) in Vietnamese patients with severe aortic valve stenosis and moderate surgical risk.

From March 2017 to December 2022, 21 patients ≥80 years and 69 patients <80 years underwent TAVR at a single center. Clinical characteristics, procedures, and outcomes at 30 days and 1 year were compared using the Valve Academic Research Consortium (VARC-2) criteria.

Patients ≥80 years had a higher prevalence of comorbidities, but no significant differences in other clinical characteristics and procedures. There were no statistically significant differences in procedural mortality (4.8% vs. 0.0%, P = 0.233), 30-day mortality (5.0% vs. 1.5%, P = 0.405), and 1-year mortality (11.8% vs. 3.7%, P = 0.241) between age groups. Key endpoints at specific time points also showed no significant differences.

TAVR in patients with aortic stenosis and moderate surgical risk had similar clinical outcomes at 30 days and 1 year according to VARC-2 criteria, with no statistically significant age-related differences (≥80 vs. <80 years). However, further studies with larger patient populations are needed to better understand the impact of age on TAVI outcomes in patients with similar characteristics.

Quelle:

Zeitschriftenreferenz:

Nguyen, KQ, et al. (2024) Transcatheter aortic valve replacement in patients aged ≥80 and <80 years with aortic valve stenosis at moderate surgical risk: results of an observational study in the Vietnamese population. Cardiovascular Innovations and Applications. doi.org/10.15212/CVIA.2024.0003.

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